An Atlas of Sarcoidosis by Violeta Mihailovic-Vucinic

By Violeta Mihailovic-Vucinic

Sarcoidosis is a posh multisytem affliction. Shortness of breath (dyspnea) and a cough that will not leave will be one of the first signs of sarcoidosis, yet sarcoidosis may also appear unexpectedly with the looks of pores and skin rashes and different dermatoses. An Atlas of Sarcoidosis: Pathogenesis, analysis and scientific positive aspects combines illustrations and medical photographs of the authors? vast practices, in order that readers have exceptional entry to a finished choice of sarcoidosis photographs. The atlas is designed to enrich and supply a visible complement to already current texts on sarcoidosis. each one organ involvement is dealt in a quick and simple to appreciate demeanour. numerous radiographic and laboratory abnormalities are then associated with the scientific beneficial properties with a view to inspire a gentle and straightforward functional integration on the bedside and to aid training pulmonologists, dermatologists and different clinicians who require a accomplished visible encyclopedia of sarcoidosis pictures.

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23 A 46-year-old patient with the chronic form of skin lesions (biopsy confirmed noncaseating sarcoid granulomas). His chest X-ray did not clear with corticosteroids. Methotrexate was administered two months ago. 25 Stage III reticular lesions, involving mainly the lower lung fields in a patient with respiratory insufficiency. The open lung biopsy showed noncaseating granulomas. He had TLCO of 45% and KCO of 32%. 27 This figure shows pneumoconiosis, not sarcoidosis. This 70-year-old patient spent more than 20 years working with silicium.

5. Loughney E, Higgins B. Pleural sarcoidosis: a rare presentation. Thorax 1997;52:200–201. 46 Atlas of Sarcoidosis 6. Durand D, Dellinger A, Guerin C, et al. Pleural sarcoidosis: one case presenting with eosinophilic effusion. Thorax 1984; 39:468–469. 7. Groman G, Castele R, Altose M, et al. Lymphocyte subpopulations in sarcoid pleural effusion. Ann Intern Med 1984; 100:75–76. 8. Hunninghake G, Crystal R. Pulmonary sarcoidosis. A disorder mediated by excess helper T lymphocytes activity at sites of disease activity.

4 A biopsy sample of the nodule in a positive reaction should demonstrate characteristic noncaseating granulomas. 5 Proportions of effector cells in normal specimen, sarcoidosis specimen, and fibrosing alveolitis specimen. 6 Bronchoalveolar lavage showing lymphocyte predominance in a sarcoidosis patient. REFERENCES 1. Lower E, Smith J, Martelo O, et al. The anemia of sarcoidosis. Sarcoidosis 1988;5:51-55. 2. Kennedy D, Yamakido M. Hematologic manifestations of sarcoidosis. Semin Resp Med 1992;13:455–458.

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