Anaphylaxis (Chemical Immunology and Allergy, Vol. 95) by Johannes Ring

By Johannes Ring

Anaphylaxis is the main dramatic and in all probability life-threatening manifestation of an immediate-type hypersensitive reaction response. even though identified for over a hundred years, it nonetheless poses many unresolved questions, and its useful administration and acute therapy are frequently extra empiric in nature than evidence-based. during this ebook, a multidisciplinary staff of specialists evaluate the state-of-the-art within the pathophysiology, epidemiology, prognosis and scientific symptomatology of anaphylaxis. Its etiology with reference to diversified elicitors similar to insect venoms, radiocontrast media, analgesics, common and native anesthetics is tested intimately. ultimately, therapy modalities for anaphylaxis are mentioned either for acute reactions and as normal administration techniques for sufferers in danger. delivering thorough and updated assurance of this often underestimated challenge, this publication is of curiosity not just to allergologists and immunologists, but in addition to all physicians and affected sufferers.

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23 Helbling A, Hurni T, Mueller UR, Pichler WJ: Incidence of anaphylaxis with circulatory symptoms: a study over a 3-year period comprising 940,000 inhabitants of the Swiss Canton Bern. Clin Exp Allergy 2004;34:285–290. 24 Antonicelli L, Bilò MB, Bonifazi F: Epidemiology of Hymenoptera allergy. Curr Opin Allergy Clin Immunol 2002;2:341–346. 25 Bonifazi F, Jutel M, Biló BM, Birnbaum J, Muller U; EAACI Interest Group on Insect Venom Hypersensitivity: Prevention and treatment of Hymenoptera venom allergy: guidelines for clinical practice.

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43 Smith PL, Kagey-Sobotka A, Blecker ER, Traystman R, Kaplan AP, Gralink H, Valentine MD, Permut S, Lichtenstein LM: Physiologic manifestations of human anaphylaxis. J Clin Invest 1980;60:1072. 44 Stark BJ, Sullivan TJ: Biphasic and protracted anaphylaxis. J Allergy Clin Immunol 1986;78:76–83. 45 Sullivan TJ: Cardiac disorders in penicillin-induced anaphylaxis: association with intravenous epinephrine therapy. JAMA 1982;248:2161. 46 Tryba M, Ahnefeld FW, Barth J, Dick W, Doenicke A, Fuchs T, Gervais H, Laubenthal H, Löllgen H, Lorenz W, Mehrkens HH, Meuret GH, Möllmann H, Piepenbrock S, Przybilla B, Ring J, Schmutzler W, Schultze-Werninghaus G, Schüttler J, Schuster JP, Sefrin P, Zander J, Zenz M: Akuttherapie anaphylaktoider Reaktionen.

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