Antisense Drug Technology - Principles, Strategies, Applns by S. Crooke

By S. Crooke

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Sample text

This move is seen as one step in a developing pattern. no chess program which even tries to use the past experience of a particular game in this way. Rather, each move is taken up anew as if it were an isolated chess problem found in a book. This technique There is forced upon programmers, since a program which carried along information on the past position of each piece would rapidly sink under the accumulating data. What is needed is a program which selectively carries is over from the past just those features which were significant in the light of its present strategy and the strategy attributed to since present programs embody its opponent.

This is the last detailed published report on the program. . same year, however, Newell, Shaw, and Simon announced: "We have written a program that plays chess," 37 and Simon, on the basis of In the this success, revised his earlier prediction: In another place, we have predicted that within ten years a computer will discover and prove an important mathematical theorem. On the basis of our experience with the heuristics of logic and chess, we are willing to add the further prediction that only moderate extrapolation is required from the capacities of programs already in existence to achieve the additional problem-solving power needed for such simulation.

This curve from success to optimism to failure can be followed in miniature in the case of Gelernter's Geometry Theorem Machine (1959). Its early success with theorems like the ports asinorum gave rise to the prediction to be totally discredited. In an article published in 1960, Gelernter explains the heuristics of his program and then concludes: first "Three years ago, the dominant opinion was that the geometry machine exist today. And today, hardly an expert will contest the would not assertion that machines will be proving interesting theorems in theory three years hence," that is, in 1963.

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